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However, given the lower intracellular GSH:GSSG ratio after IL-13 stimulation, it is difficult to determine the proportionate role that loss of GSH plays in downstream T2-pathway mRNA/protein expression

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Recruitment of cBAF and PBAF complexes is required for transcription of SLC7A11 SLC7A11 To determine the mechanism underlying the attenuation of SLC7A11 mRNA expression in SWI/SNF-deficient cancer cells, we investigated the involvement of SMARCA4 (a component of cBAF, PBAF, and ncBAF) and SMARCB1 (a component of cBAF and PBAF) in transcriptional upregulation of SLC7A11

Murad HY, Yu H, Luo D, et al

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